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Arch Otolaryngol Head Neck Surg. 2006;132:1386-1387.

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Diagnosis: Schwannoma of the tongue

First described as a neurinoma by Verocay¹ in 1910, a schwannoma is a slow-growing tumor that arises from the Schwann cells encapsulating peripheral nerves. It is also commonly referred to by a variety of names, including neurilemoma, neurolemmoma, and perineural fibroblastoma, but schwannoma is the preferred pathologic term, as it most specifically describes the main cells that compose the tumor. Schwannomas have a peak incidence in the second through fifth decades of life and have no predilection for sex or race. They rarely demonstrate malignant change and, along with neurofibromas, are the most common nerve sheath tumors.

Because schwannomas are derived from the encasing cells of peripheral nerve fibers, they may affect any portion of the peripheral nervous system, but it has been estimated that up to 25% to 45% of cases present in the head and neck.² The most well-known schwannoma involves the vestibular portion of . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2006;132(12):1384.
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