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Arch Otolaryngol Head Neck Surg. 2005;131:742.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Rhinocerebral mucormycosis with cavernous sinus thrombosis

The CT scan showed an aggressively destructive lesion in the lateral sphenoid sinus wall, with diffuse induration of the orbital soft tissues and expansion of the cavernous sinus. It also showed opacification of the paranasal sinuses. The differential diagnosis of a destructive lesion at this location falls into 2 categories: neoplastic or infectious/inflammatory diseases. The neoplastic category includes malignant neoplasms with metastasis to the cavernous sinus, lymphoma, and perineural or direct extension from nasopharyngeal carcinoma. The infectious/inflammatory category includes intracranial complications due to sinusitis. Invasive fungal, as well as bacterial, sinusitis must also be considered. Immediate biopsy via an endoscopic approach and culture are mandatory. Early and accurate treatment may resolve the cranial neuropathies.

Mucormycosis can manifest as 6 different syndromes: rhinocerebral, pulmonary, gastrointestinal, central nervous system, subcutaneous, and disseminated forms. Rhinocerebral mucormycosis accounts for 80% to 90% of mucormycosis infection.^1-3 It frequently originates from opportunistic invasion of the nasal . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2005;131(8):738.
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