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Arch Otolaryngol Head Neck Surg. 2005;131:736.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Mandibular metastasis of hepatocellular carcinoma (HCC)

Hepatocellular carcinoma usually metastasizes to the lungs, adrenal glands, and regional lymph nodes.¹ Metastatic spread to bone is uncommon. Because the jaws do not contain any lymphatic vessels, spread to this site occurs hematogenously. Metastatic HCC to the jaws occurs most frequently in the sixth and seventh decades of life and is especially prevalent among males. Although the most common symptoms and signs are pain and swelling in the affected regions, even paresthesia of the lower lip and chin has been reported.²

Computed tomography of the head and neck in the present case revealed a contrast-enhanced mass, with destruction of the left mandibular body (Figure 1). Microscopic examination of the biopsy specimens (Figure 2 and Figure 3) demonstrated epithelial cells with abundant cytoplasm and prominent nucleoli growing in a partly solid and partly trabecular pattern. The tumor cells in the trabecular areas lined sinusoidlike spaces filled . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2005;131(8):735.
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