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Arch Otolaryngol Head Neck Surg. 2005;131:644.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Chondroid syringoma

Originally described as a mixed tumor of the skin by Billroth¹ in 1859, this uncommon benign neoplasm was called chondroid syringoma by Hirsch and Helwig² in 1961 to more accurately describe the lesion’s cellular characteristics. Hirsch and Helwig proposed the following defining histologic characteristics of the lesion: (1) nests of cuboidal or polygonal cells; (2) tubuloalveolar structures lined by 2 or more rows of cuboidal cells; (3) ductal structures composed of 1 or 2 rows of cuboidal cells; and (4) occasional keratin cysts. The tumor is thought to arise from apocrine and/or eccrine glands.³ Histologic analysis of a chondroid syringoma demonstrates nests or cords of epithelial cells set in a stromal matrix. The epithelial cells are usually cuboidal, but they can have a variable cytologic appearance (eg, eccrine, apocrine, sebaceous, mucinous, simple glandular, or squamous). They can be oriented in sheets and whorls, with glandular and ductal . . . [Full Text of this Article]

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