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  Vol. 131 No. 3, March 2005 TABLE OF CONTENTS
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  Clinical Problem Solving: Pathology
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Pathology Quiz Case—Diagnosis

Arch Otolaryngol Head Neck Surg. 2005;131:272-273.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Ossifying fibroma of the maxilla presenting with associated sinusitis and orbital complications

Ossifying fibroma is a benign fibro-osseous lesion that most commonly occurs in the bones of the craniofacial skeleton. Seventy-five percent of these lesions are found in the mandible.1-2 Ossifying fibroma of the maxilla is uncommon. Most diagnoses are made in the third or fourth decade of life, although onset can occur at any age. There is a slight predilection for women (female-male ratio, 1.6:1.0).3

Because of its expansile nature, ossifying fibroma clinically presents as jaw or facial asymmetry, displacement of teeth or hard palate, proptosis, nasal obstruction, or, rarely, sinusitis with or without eye pain.4 Grossly, ossifying fibromas are firm, gritty, gray, tan, or white masses usually ranging from 5 mm to 10 cm in diameter. Histopathologically, the lesions are composed of randomly distributed, osteoblast-lined (Figure 1, arrow), lamellar bone spicules within a background of fibrous stroma. The bone spicules are rarely completely mature. The fibrous stroma may . . . [Full Text of this Article]



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