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Arch Otolaryngol Head Neck Surg. 2005;131:174-175.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cervical neuroblastoma (NB)

Neuroblastoma is a malignant tumor consisting of undifferentiated neuroectodermal cells of neural crest origin. It is the most common malignancy of infancy and the most frequently diagnosed extracranial solid tumor in children younger than 5 years.^1-2 It is an aggressive neoplasm that is capable of both hematogenous and lymphatic metastasis, and it is responsible for 15% of pediatric cancer-related deaths despite representing only 8% to 10% of pediatric malignancies.^{1, 3} The tumors are derived from neural crest cells associated with the sympathetic nervous system, and most are located in the adrenal medulla (75%-90%) and thoracoabdominal sympathetic ganglia (10%-15%).^4-5 Only 2% to 5% of primary NBs are of cervical origin, and many of the NBs that present in the head and neck region represent metastatic disease.^4-5

The clinical presentation of NB is variable and depends on the tumor’s location. Children with head and neck NB may present with a palpable neck mass, . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2005;131(2):172.
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