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Pathology Quiz Case 2: Diagnosis
Arch Otolaryngol Head Neck Surg. 2005;131:1123-1124.
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Diagnosis: Nodular fasciitis
Nodular fasciitis, which was first described by Konwaler et al1 in 1955, is a benign and quasineoplastic proliferation of fibroblasts that is often mistaken for a sarcoma owing to its rapid growth, rich cellularity, and mitotic activity. Synonymous terms such as pseudosarcomatous fasciitis, proliferative fasciitis, infiltrative fasciitis, and nodular fibrositis have been used in the literature to describe this fibrous tissue tumor.2 Although the exact pathogenesis remains unknown, it is thought that the lesion represents a self-limiting, reactive process rather than a true neoplasm. With 80% to 90% of lesions occurring outside the head and neck, most patients report a history of a rapidly growing mass over a 1- to 2-week time frame.3-4 There is associated soreness, tenderness, or slight pain in about 50% of cases, but a history of inciting trauma is elicited in no more than 10% to 15% of cases.4 On further questioning of . . . [Full Text of this Article]
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Pathology Quiz Case 2
Ian K. McLeod, Rebecca Christensen, and M. Pete Sorensen
Arch Otolaryngol Head Neck Surg. 2005;131(12):1121.
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