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Arch Otolaryngol Head Neck Surg. 2005;131:1118.

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Diagnosis: Benign osteoblastoma

Benign osteoblastoma, a rare benign tumor of the bone, was first described by Virchow¹ in 1863. Osteoblastomas account for fewer than 1% of all bone tumors and 3% of all benign bone tumors.² They usually occur in the vertebrae and in long tubular bones.³ The skull is involved in fewer than 15% of cases.⁴ The male-female ratio is 2:1, and most cases occur in the second decade of life.⁵

Osteoblastomas are divided into 2 types: osteoid and periosteal. In the osteoid type, the tumor arises from the subcortical or medullary portion of the bone and usually affects the long bones and vertebrae. On rare occasions, the tumor may arise from the periosteum and have eccentric or centrifugal growth, giving rise to the periosteal type.⁶ The differential diagnosis of osteoblastomas includes not only other bony neoplasms, such as osteoma, osteoid osteoma, and osteogenic sarcoma, but also fibro-osseous lesions, such as ossifying . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2005;131(12):1116.
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