This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Diagnosis  • Inflammatory Disease of Head & Neck  • Pathology of Head & Neck  • Alert me on articles by topic

Arch Otolaryngol Head Neck Surg. 2004;130:890.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cutaneous nasal sarcoidosis

Sarcoidosis is a chronic granulomatous disease of unknown etiology, frequently involving the respiratory tract. Its incidence is approximately between 6 and 10 per 100 000, with a slight female predominance and a peak age at onset of between 20 and 40 years. Sarcoidosis has the greatest incidence in Sweden. In the United States, it more commonly affects African Americans.

Histologically, sarcoidosis is characterized by multiple epithelioid and giant cell granulomas. The granulomas are formed by tight aggregates of epithelioid histiocytes; they are characteristically noncaseating and are surrounded by a sparse mixed inflammatory infiltrate. Giant cells, typically of Langerhans type, are usually present and may contain intracytoplasmic inclusions, including star-shaped structures called asteroid bodies and calcific laminated structures called Schaumann bodies. Special stains for infectious organisms are negative in sarcoid granulomas.

Constitutional symptoms such as fevers, weight loss, anorexia, and malaise are usually present. The disease can affect all organs, but more . . . [Full Text of this Article]

RELATED ARTICLE

Pathology Quiz Case 1
Trang Vo-Nguyen, David Hom, and Stefan Pambuccian
Arch Otolaryngol Head Neck Surg. 2004;130(7):888.
EXTRACT | FULL TEXT