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  Vol. 130 No. 6, June 2004 TABLE OF CONTENTS
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  Clinical Problem Solving: Radiology
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 •Neoplasms of Head & Neck
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Radiology Quiz Case 1—Diagnosis

Arch Otolaryngol Head Neck Surg. 2004;130:798-799.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Nasopharyngeal carcinoma (NPC)

Computed tomography of the neck unsuspectingly revealed a large inhomogeneous soft tissue mass in the nasopharynx, with extension into the posterior nasal cavity (Figure 2). The mass diffusely deformed the nasopharynx and oropharynx and resulted in lateral bowing of the pterygoid plates on both sides. A subsequent cervical lymph node biopsy specimen demonstrated cytokeratin-positive tumor cells. The findings of other immunoperoxidase staining were consistent with NPC.


 
Figure appears in full text version.
Figure 2.


Nasopharyngeal carcinoma is a malignant tumor with a bimodal age distribution: early occurrences are observed between 10 and 20 years of age and later occurrences between 40 and 60 years of age.1 It is the most common pediatric epithelial cancer; however, it accounts for only 1% to 2% of childhood malignancies.2 The annual incidence is 1:100 000 in children in North America. Hawkins et al,2 using the Pediatric Oncology Group Rare Tumor Registry from 1973 to 1988, found 27 pediatric patients . . . [Full Text of this Article]







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