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  Vol. 130 No. 6, June 2004 TABLE OF CONTENTS
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  Clinical Problem Solving: Pathology
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 •Neoplasms of Head & Neck
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Pathology Quiz Case 1—Diagnosis

Arch Otolaryngol Head Neck Surg. 2004;130:792-793.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Acinic cell carcinoma of the parotid gland with ductal extension

Acinic cell carcinoma is an uncommon tumor of salivary gland origin. It comprises 5% to 11% of all salivary gland cancers, with salivary gland carcinomas representing 0.3 to 0.9% of all cancers in the United States.1 Acinic cell carcinomas are almost exclusively found in the parotid gland, although rare occurrences in the submandibular and minor salivary glands have been reported. There is a 2:1 female-male predominance, and the highest incidence occurs in the fourth to sixth decades of life. Multicentricity within the parotid gland is noted in 2% to 5% of cases. Acinic cell carcinoma ranks second, after Warthin tumor, for bilaterality among parotid neoplasms, and it can have a similar intranodal (parotid and periparotid) origin. It ranks as the third most common epithelial malignancy of the salivary glands in adults and, according to Batsakis et al,2 is second only to mucoepidermoid carcinoma among malignancies of the parotid gland in . . . [Full Text of this Article]



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