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  Vol. 130 No. 4, April 2004 TABLE OF CONTENTS
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  Clinical Problem Solving: Pathology
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 •Oncology
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Pathology Quiz Case 1—Diagnosis

Arch Otolaryngol Head Neck Surg. 2004;130:476-477.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Small cell carcinoma (SmCC) of the parotid gland

Small cell carcinoma, which is most often a pulmonary neoplasm, represents 25% to 35% of primary lung tumors.1 Extensive lung SmCC has an 8-month median survival rate, and limited-stage disease has a 5-year survival rate of 5% to 10% despite the standard treatment of combined chemotherapy and radiation therapy.2 Only 4% of SmCCs arise from extrapulmonary sites,3 including the head and neck region, gastrointestinal tract, pancreas, uterine cervix, endometrium, bladder, prostate, kidneys, thymus, and breast.3 The most common location of SmCC in the head and neck is the larynx.4 Small cell carcinoma can also involve the minor salivary glands, nasal cavity, paranasal sinuses, major salivary glands, and, rarely, trachea, oral cavity, and oropharynx.4-5 Small cell carcinoma of the major salivary glands most commonly develops in the parotid gland.3

Histopathologic examination of our patient's parotid mass showed poorly differentiated cancer with sheets of closely packed dark cells with focal nuclear crushing, . . . [Full Text of this Article]



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RELATED ARTICLE

Pathology Quiz Case 1
Hari Nadiminti, Giovana R. Thomas, and Jacinto Regalado
Arch Otolaryngol Head Neck Surg. 2004;130(4):474.
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