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Arch Otolaryngol Head Neck Surg. 2004;130:240.

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Diagnosis: Atypical fibroxanthoma of the auricle

Atypical fibroxanthoma (AFX), which was first described by Helwig¹ in 1961, is a rare fibrohistiocytic tumor that is generally known as a superficially situated low-grade sarcoma with a low recurrence rate.² It is also called pseudosarcoma, paradoxical fibrosarcoma, pseudosarcomatous dermatofibroma, and pseudosarcomatous reticulohistiocytoma.³ It typically presents as a nodular skin lesion on sun-exposed areas of the head and neck^2-3 and is most commonly seen on the nose, auricles, cheeks, and scalp. Occupational or therapeutic exposure to radiation may also be an etiologic factor.³ Atypical fibroxanthoma is histologically composed of spindle-shaped or round cells with prominent pleomorphism, nuclear atypia, and a high mitotic rate.^3-4 It is also characterized by cells with bizarre cytologic atypia arranged in a haphazard or vague fascicular pattern.³

Morphologically, AFX presents as a fast-growing, often exophytic, polypoid, ulcerated lesion, generally less than 2 cm in diameter, but this picture is not diagnostic. The . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2004;130(2):238.
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