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Arch Otolaryngol Head Neck Surg. 2004;130:1440-1441.

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Diagnosis: Cutaneous angiosarcoma

Angiosarcoma is an uncommon malignant mesenchymal tumor that can occur in any region of the body. Approximately 50% of all angiosarcomas develop in the head and neck, but they account for fewer than 0.1% of all the malignant neoplasms that occur in that area.¹ Cutaneous angiosarcoma commonly affects elderly white men. The estimated male-female ratio is 3:1. The median age at onset is approximately 64 years (age range, 6 months to 92 years). Although there is some suggestion that younger patients tend to do better, no studies show a statistically significant association between age and outcome.²

Little is known about the cause of angiosarcomas. Several associations have been made. A common theory proposes that some form of previous connective tissue damage may be a pathogenetic factor. Actinic damage due to sun exposure has been suggested; however, many lesions arise from the scalp of patients with a full head of hair.³ . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2004;130(12):1439.
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