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Arch Otolaryngol Head Neck Surg. 2004;130:1440.

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Diagnosis: Teflon granuloma

Despite the introduction of laryngeal framework surgery for the treatment of unilateral vocal cord paralysis, Teflon injection is still advocated in certain medical centers in view of the simplicity of the procedure.^1-2 Although the frequency of its use has declined recently, we still encounter patients with problems related to Teflon injection years after undergoing the procedure.

Polytef, or polytetrafluoroethylene, was first discovered in 1938 as a strong, bonded, inert polymer.³ In 1962, Arnold⁴ introduced the injection of Teflon paste as a space-occupying substance for the medialization of a paralyzed vocal cord fixed in the lateral position. Quantitative measures of laryngeal function after Teflon injection have shown an irregular glottic closure pattern, edema, and erythema of the paralyzed true vocal fold, with hypertrophy and hyperfunction of the false vocal fold.⁵ Technical errors in Teflon injection, such as overinjection, injecting too deeply, or injecting too close to the vocal cord, can result . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2004;130(12):1438.
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