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Pathology Quiz Case 1Diagnosis
Arch Otolaryngol Head Neck Surg. 2004;130:1338.
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Diagnosis: Angiolymphoid hyperplasia with eosinophilia
Angiolymphoid hyperplasia with eosinophilia is a rare disease that is characterized by benign, locally proliferating lesions composed of vascular channels with a surrounding infiltrate of lymphocytes and eosinophils. The lesions occur predominantly in the skin of the head and neck area and appear clinically as persistent, pruritic, erythematous nodules that differ in size and tend to bleed after irritation.1-3 The term angiolymphoid hyperplasia with eosinophilia was first introduced by Wells and Whimster4 in 1969. Nowadays, angiolymphoid hyperplasia with eosinophilia, together with some other related vascular lesions, is classified under the general term epithelioid hemangioma.5
The disease may occur at any age but is most commonly seen in middle-aged adults. There is a female predominance of 2:1. The lesions are especially common in the periauricular region. Fifty percent of the patients develop multiple lesions in the same area.2
Controversy exists regarding the etiology of these lesions. Some authors theorize that . . . [Full Text of this Article]
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Pathology Quiz Case 1
Femke van der Steenstraten, J. Alexander de Ru, Hein Leverstein, and Pieter J. Slootweg
Arch Otolaryngol Head Neck Surg. 2004;130(11):1336.
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