This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Pathology of Head & Neck  • Diagnosis  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Otolaryngol Head Neck Surg. 2004;130:1234.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Kikuchi-Fujimoto disease (KFD)

Kikuchi-Fujimoto disease, or necrotizing lymphadenitis, is a rare benign, self-limiting syndrome that was first described independently by Kikuchi and Fujimoto in 1972. It is prevalent mainly in Asian countries. However, cases have recently been reported from most parts of the world.

The exact pathogenesis of KFD is unknown. The disease has distinctive pathologic features that separate it from toxoplasmosis.¹ Although it has been suggested that KFD can be caused by infectious agents such as Yersinia enterocolitica, herpesvirus, cytomegalovirus, and varicella-zoster, parainfluenza, and Epstein-Barr viruses, recent studies have failed to confirm this theory.² The presence of cytoplasmic tubuloreticular structures, like those seen in systemic lupus erythematosus, suggests that abnormal cell-mediated immune response is an etiologic factor.³ Lin et al⁴ theorized that the absence of monoclonal T-cell receptor rearrangements excludes the possibility of T-cell lymphoma and that the presence of oligoclonal pattern is evidence of a benign immune reaction.

Kikuchi-Fujimoto disease . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Pathology Quiz Case
P. Gopalan, M. Kumar, D. W. Aird, and W. Williams
Arch Otolaryngol Head Neck Surg. 2004;130(10):1233-1234.
EXTRACT | FULL TEXT