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Arch Otolaryngol Head Neck Surg. 2003;129:1136.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Nasal T/NK-cell lymphoma

Clinical manifestations of nasal T/NK-cell lymphomas may simulate those of other disease entities, and inadequate nasal biopsies may lead to nonspecific histopathologic pictures; therefore, early diagnosis of these lymphomas is a real challenge for both otolaryngologists and pathologists. Nasal T/NK-cell lymphomas usually present as extremely destructive lesions over the nasal cavities, paranasal sinuses, or nasopharynx, showing a necrotic and angioinvasive histopathologic pattern. In the past, they were included under the nebulous and descriptive term lethal midline granuloma.¹ With the advance of immunohistochemical analysis and a growing understanding of sinonasal lymphomas, nasal T/NK-cell lymphomas could be distinguished from other groups of lethal midline granulomas, including infectious (such as tuberculosis) and noninfectious (such as WG) lesions.²

While sinonasal lymphomas are rare among Western populations, they are of significantly higher incidence in the Asian world, accounting for 2.6% to 6.7% of all non-Hodgkin lymphomas. It is interesting that 90% of the sinonasal . . . [Full Text of this Article]

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Arch Otolaryngol Head Neck Surg. 2003;129(10):1135-1136.
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