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Pathology Quiz Case
Hung-Li Chen, MD;
Po-Wen Cheng, MD;
Chien-Chen Tsai, MD
National Taiwan University (Dr Chen) and Far Eastern Memorial Hospital (Drs Cheng and Tsai), Taipei, Taiwan
Arch Otolaryngol Head Neck Surg. 2003;129:1135-1136.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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A 71-YEAR-OLD woman presented with a 3-year history of intractable nasal blockage with fetid purulent discharge, accompanied by intermittent blood-tinged postnasal dripping and low-grade fever. She denied weight loss or cold sweating. Nasal Wegener granulomatosis (WG) was diagnosed at another medical center because the findings of a nasal biopsy were thought to be consistent with that diagnosis, although the results of cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) tests were negative. After receiving steroid therapy, without relief of symptoms, the patient was referred to our center for further evaluation and treatment.
On physical examination, she was afebrile but appeared chronically ill. Otoscopy and tympanocentesis revealed otitis media with serous effusion in the left ear. In addition to posterior septal perforation, rhinoscopy demonstrated ulcerative and necrotic mucosa covered by crust and mucopus mainly in the posterior nasal cavities and nasopharynx (Figure 1). . . . [Full Text of this Article]
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