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Arch Otolaryngol Head Neck Surg. 2002;128:464.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Carcinoma arising in a TGDR is rare. It is usually diagnosed after the excision of a presumed benign thyroglossal duct cyst. A 1994 review reported 155 cases in the world literature.¹ Of these, approximately 80% were papillary or a follicular variant of papillary thyroid cancer. The same review quoted from the Dutch registry a TGDCa incidence of 0.48% (2/413). Unfortunately, since the literature consists of multiple case reports, long-term follow-up on a large series of patients is lacking. Well-differentiated carcinomas of the thyroid gland require long-term follow-up for the survival and disease-free interval data to be valuable. The extrapolation of data from well-differentiated thyroid cancers to TGDCa may not be valid.

The prevalence of TGDCa in the Mayo Clinic series was 0.7% (12/741).² Of these 12 patients, 9 had a thyroidectomy during their treatment. Three of these had thyroidal foci of cancer. One of these had a 1.5-cm focus of . . . [Full Text of this Article]

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