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Arch Otolaryngol Head Neck Surg. 2001;127:461-462.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

There is no prospective randomized study with long-term follow-up to guide the surgeon when treating patients with well-differentiated thyroid cancer, and unless a tumor marker with predictive value is discovered, this conundrum will not be settled in the near future. In the absence of a definitive study, I believe that the most logical approach to this tumor is to use risk factor analysis models such as AMES¹ or the classifications proposed by Shah et al² and Shaha et al.³ It is very clear that well-differentiated thyroid cancer can act very differently depending on a patient's risk-factor classification. Low-risk patients tend to do very well regardless of the extent of thyroidectomy, and high-risk patients tend to do poorly even with aggressive treatment. Although papillary thyroid cancer is frequently multifocal, the significance of microscopic disease in the contralateral lobe is questionable. The patient presented in the clinical challenge falls into the low-risk . . . [Full Text of this Article]

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