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Aspirin Desensitization for Chronic Hyperplastic Sinusitis, Nasal Polyposis, and Asthma Triad
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We read with interest the article by Gosepath et al1
in which they reported their clinical experience with aspirin desensitization
in subjects with chronic hyperplastic sinusitis and nasal polyposis. Chronic
hyperplastic sinusitis/nasal polyposis is a significant medical problem, often
with few consistent therapeutic interventions. As Gospath and colleagues'
study demonstrated, aspirin desensitization may be a safe and effective therapeutic
procedure, but at present it is greatly underused. We therefore wish to submit
our clinical experience with this procedure and confirm the positive results
that were reported by Goseparth and colleagues.
From 1996 through 1998, a total of 53 aspirin desensitizations were
performed at the National Jewish Medical and Research Center, Denver, Colo,
on 41 subjects (12 desensitizations were performed a second time owing to
pregnancy and noncompliance). The procedures were safe, and there were no
hospital admissions or respiratory arrests. One patient had a delayed bronchospastic
reaction that required treatment . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Management Options for Patients with Aspirin and Nonsteroidal Antiinflammatory Drug Sensitivity
Knowles et al.
The Annals of Pharmacotherapy 2007;41:1191-1200.
ABSTRACT
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