In September 1997 we participated in the Croatian Congress of Pharmacology in Rijeka, Croatia, with a poster presenting our work at the Clinic of Otorhinolaryngology, Clinical Hospital Centre of Rijeka entitled "Local Application of Ciprofloxacin in Therapy of Long-Lasting Otorrhea."
The purpose of our study was to investigate the efficiency of the simplified therapy of otorrhea by the application of ciprofloxacin once daily, and to compare the obtained results with the results from the literature where the same drug was administered 2 to 4 times daily.
The advantages of topical ciprofloxacin have already been confirmed by other authors.1-7 They have proved its efficiency with negligible adverse effects.
Until recently, there was no otologic preparation of ciprofloxacin on the market, and ampules for parenteral therapy had to be diluted for local application.This was not only impractical but also caused the great dosage differences used by different authors.1-7
In the August 1994 . . . [Full Text of this Article]