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Electrophysiological Study of the Effect of Sodium Salicylate Upon the Cochlea
Curt Mitchell, PhD;
Robert Brummett, PhD;
Donna Himes;
Jack Vernon, PhD
Arch Otolaryngol. 1973;98(5):297-301.
Abstract
Sodium salicylate was shown to have no effect on the alternating current cochlear potential and to reduce the neural evoked potential. This effect is reversible. It is postulated that sodium salicylate does not affect the hair cells of the cochlea but does affect the afferent auditory nerve impulses. This mechanism is thought to account for most of the hearing loss due to salicylates.
Author Affiliations
Portland, Ore
From the Kresge Hearing Research Laboratory, Department of Otolaryngology, University of Oregon Medical School, Portland, Ore.
Footnotes
Accepted for publication Sept 27, 1972.
Reprint requests to Kresge Hearing Research Laboratory, Department of Otolaryngology, University of Oregon Medical School, Portland, OR 97401 (Dr. Mitchell).
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