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H. Schapiro, PhD; C. W. Gross, MD; T. Nakamura, MD; L. D. Wruble, MD; L. G. Britt, MD

Arch Otolaryngol. 1971;94(1):36-39.

Abstract
Gastric cannulae were placed in the stomach of four dogs. The acid output per hour was determined after (1) the subcutaneous injection of 0.1 mg histamine (base), (2) the subcutaneous injection of 1.0 mg histamine (base), and (3) the intravenous injection of 1.0 unit/kg of insulin. The pepsin concentration was also determined after the intravenous injection of 1.0 unit/kg of insulin. Following bilateral labyrinthectomy the gastric secretory studies were repeated at intervals. There was a depression of the acid output and the pepsin concentration in all dogs, to all the gastric stimuli, over a four-month period.

Author Affiliations
Memphis, Tenn

From the departments of anatomy (Dr. Schapiro), otolaryngology and maxillofacial surgery (Drs. Gross and Nakamura), medicine (Dr. Wruble), (Division of Gastroenterology) and surgery (Dr. Britt), University of Tennessee Medical Units, and the Research Laboratories, VA Hospital, Memphis, Tenn.

Footnotes
Accepted for publication Feb 16, 1971.

Reprints to University of Tennessee College of Medicine, Memphis 38103 (Dr. Gross).

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