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Combination of Autologous Fascia Lata and Fat Injection Into the Vocal Fold via the Cricothyroid Gap for Unilateral Vocal Fold Paralysis
You Cheng, MD;
Ze-qing Li, MD;
Jin-zhong Huang, MD;
Fei Xue, MD;
Man-jie Jiang, MD;
Kun-min Wu, MS;
Qiu-ping Wang, MD
Arch Otolaryngol Head Neck Surg. 2009;135(8):759-763.
Objectives To apply the technique of injection of a combination of autologous fascia lata and fat into the vocal fold via the cricothyroid gap for unilateral vocal fold paralysis and to evaluate the therapeutic effect in 12 patients who underwent the procedure.
Design Retrospective analysis of 12 patients.
Setting Academic research.
Patients A mixture of autologous fascia lata and fat was injected into the thyroarytenoid muscle of the paralyzed vocal fold in 12 patients.
Main Outcome Measures Videolaryngostroboscopy was performed to observe the changes to the vocal fold. The patients' phonatory function before and after surgery was assessed by computerized acoustic analysis and by blinded perceptual evaluation.
Results Videolaryngostroboscopy demonstrated that the paralyzed vocal folds in these patients were pushed medially after the procedure. Statistically significant improvements were found in the perturbation measurements (jitter and shimmer), harmonics to noise ratio, and maximum phonation time. Ratings by a panel of voice experts also showed each voice to be statistically significantly improved after the procedure. No complications were noted.
Conclusion A combination of autologous fascia lata and fat injected into the vocal fold for unilateral vocal fold paralysis is a safe and effective therapy.
Author Affiliations: Department of Otolaryngology–Head and Neck Surgery, Jinling Hospital, Clinical Medical College of Nanjing University, Nanjing (Drs Cheng, Li, Xue, Jiang, and Wang and Mr Wu), and Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou (Dr Huang), China.
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