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  Vol. 135 No. 4, April 2009 TABLE OF CONTENTS
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Voice-Related Quality of Life After Treatment of Laryngeal Cancer

Nobuhiko Oridate, MD, PhD; Akihiro Homma, MD, PhD; Seigo Suzuki, MD, PhD; Yuji Nakamaru, MD, PhD; Fumiyuki Suzuki, MD, PhD; Hiromitsu Hatakeyama, MD, PhD; Shigenari Taki, MD; Tomohiro Sakashita, MD; Noriko Nishizawa, MD, PhD; Yasushi Furuta, MD, PhD; Satoshi Fukuda, MD, PhD

Arch Otolaryngol Head Neck Surg. 2009;135(4):363-368.

Objective  To determine patient-perceived voice-related quality of life in patients treated with various methods based on the results of Voice-Related Quality of Life (VRQOL) and Voice Handicap Index-10 (VHI-10) questionnaires.

Design  The VRQOL and VHI-10 questionnaires.

Setting  University hospital.

Patients  One hundred thirty-seven patients who had received definitive treatment of laryngeal cancer were followed-up at Hokkaido University Hospital, Sapporo, Japan, and were alive with no evidence of malignancy at the time of the survey.

Main Outcome Measure  Patient-perceived voice-related quality of life based on the results of the VRQOL and VHI-10 questionnaires.

Results  The mean VRQOL scores for patients who had undergone radiotherapy (n = 63), chemoradiotherapy (n = 29), laser surgery (n = 14), or total laryngectomy (n = 27) as final treatment of laryngeal cancer were 92.6, 92.9, 85.5, and 68.4, respectively; the mean VHI-10 scores were 2.87, 2.34, 5.43, and 11.26, respectively.

Conclusion  The VRQOL and VHI-10 questionnaires are important in judging the overall effectiveness of treatment options for laryngeal cancer.


Author Affiliations: Department of Otolaryngology–Head and Neck Surgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan.



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