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Role of Tonsillectomy in PFAPA Syndrome
Kevin K. Wong, MD;
Jane C. Finlay, MD, FRCPC;
J. Paul Moxham, MD, FRCSC
Arch Otolaryngol Head Neck Surg. 2008;134(1):16-19.
Objective To examine the efficacy of tonsillectomy in ameliorating symptoms and preventing recurrence of episodes in children with PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, and adenitis).
Design Retrospective case series.
Setting Tertiary care children's hospital.
Patients Patients who presented to a major tertiary teaching hospital in Vancouver, British Columbia, Canada, between 2000 and 2004 with the diagnosis of PFAPA syndrome or for whom the diagnosis was made on their initial consultation.
Intervention Tonsillectomy.
Main Outcome Measures Resolution of symptoms at 3, 12, and 24 months after tonsillectomy.
Results Eight of the 9 patients achieved complete remission within 3 months. In the remaining patient, the frequency of episodes decreased from every 2 weeks to once every 3 to 4 months. This patient eventually had resolution of symptoms at 2 years after tonsillectomy. No complications resulted from the tonsillectomy.
Conclusion Tonsillectomy is a viable treatment option for patients with PFAPA syndrome.
Author Affiliations: Division of Otolaryngology, Department of Surgery (Drs Wong and Moxham), and Division of General Pediatrics and Infectious Diseases, Department of Pediatrics (Dr Finlay), British Columbia's Children's Hospital, Vancouver, British Columbia, Canada.
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