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Injection Laryngoplasty, Thyroplasty, or Nerve Reinnervation?

J. Andrew Sipp, MD; Joseph E. Kerschner, MD; Nicole Braune, RN; Christopher J. Hartnick, MD

Arch Otolaryngol Head Neck Surg. 2007;133(8):767-771.

Objective  To review surgical interventions for pediatric unilateral vocal fold immobility (UVFI).

Design  Retrospective medical chart review.

Setting  Two tertiary academic centers.

Patients  All children who underwent vocal fold medialization for dysphonia, with or without aspiration, from January 2004 to September 2006.

Interventions  Injection laryngoplasty, ansa cervicalis–recurrent laryngeal nerve anastomosis, or thyroplasty.

Main Outcome Measures  Age, sex, intervention, etiology, time from onset of UVFI to surgery, subjective success in improving voice, subjective duration of improvement, and complications.

Results  Twenty-seven procedures were performed in 15 patients (mean age, 10.6 years). Nineteen injection laryngoplasties, 3 thyroplasties (1 bilateral), 2 ansa cervicalis–recurrent laryngeal nerve reinnervation procedures, 1 adduction arytenoidopexy, and 1 cricothyroid joint subluxation were performed. Causes of UVFI included thoracic surgery in 6 cases (40%), prolonged intubation in 4 (26%), central nervous system neoplasm in 3 (20%), unknown etiology in 1 (7%), and anoxic brain injury in 1 (7%). The mean duration from onset of symptoms to treatment was 47 months. There was 1 surgical complication (postoperative aspiration pneumonia following thyroplasty while the patient was under local anesthesia). Parents reported a satisfactory outcome in all cases.

Conclusions  Injection laryngoplasty, thyroplasty, and nerve reinnervation can be performed in pediatric patients with good outcomes and an acceptable safety profile. This article describes the experiences of 2 institutions with phonosurgery for UVFI in children and provides insight into the advantages and disadvantages of each procedure. Prospective studies, with validated quality-of-life measurements, are needed to greater clarify the role of different types of phonosurgery in children with UVFI.

Author Affiliations: Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston (Drs Sipp and Hartnick); and Department of Pediatric Otolaryngology, Medical College of Wisconsin, Milwaukee (Dr Kerschner and Ms Braune).