Vascular Evaluation in Laryngeal Diseases
Comparison Between Contact Endoscopy and Laser Doppler Flowmetry
Michihiko Sone, MD;
Eisuke Sato, MD;
Hideo Hayashi, MD;
Yasushi Fujimoto, MD;
Tsutomu Nakashima, MD
Arch Otolaryngol Head Neck Surg. 2006;132:1371-1374.
Objective To determine the efficacies of 2 methods for evaluating vascular changes in laryngeal diseases.
Design Prospective comparative study.
Setting University hospital.
Patients Twenty-four adults planning to undergo laryngomicrosurgery for unilateral lesions in their vocal cords.
Intervention Vascular evaluation was performed using contact endoscopy and laser Doppler flowmetry during laryngomicrosurgery.
Main Outcome Measures Morphological and physiological variables of the vascular changes.
Results Contact endoscopy examinations revealed changes in the fine vascular network patterns in the vocal cords. Hypervascularity was present in patients with polyps but not in those with nodules, and the degree of vascularity was variable in patients with malignant neoplasms. Patients with papillomas and patients in the postradiation therapy group showed hypovascularity with losses in the capillary network. Laser Doppler flowmetry revealed high mean blood flows in patients with polyps, dysplasia, and malignant neoplasms, whereas patients with papillomas and those in the postradiation therapy group had low blood flows. The variables measured by laser Doppler flowmetry and endoscopy were strongly correlated.
Conclusion Evaluations of morphological and physiological changes of vascularity in laryngeal diseases are important for understanding their pathophysiology, and combining contact endoscopy and laser Doppler flowmetry is useful in such evaluations.
Author Affiliations: Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
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