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Marina Boruk, MD; Boris Chernobilsky, MD; Richard M. Rosenfeld, MD, MPH; Gady Har-El, MD

Arch Otolaryngol Head Neck Surg. 2005;131:605-609.

Objective  To determine if age alone is a prognostic indicator of surgical outcomes for major head and neck procedures.

Design  Retrospective cohort study over a 4-year period.

Setting  Academic referral center, institutional practice, hospitalized care.

Patients  Included in this study were patients who had undergone ablative, reconstructive, and other major surgical procedures of the head and neck, including neck dissection, laryngectomy, maxillectomy, thyroidectomy with lymphadenectomy, and composite resection of the oral cavity with reconstruction, for both malignant and benign disease.

Main Outcome Measures  Patient data and intraoperative and postoperative course factors were recorded. Comorbidity was graded using an Adult Comorbidity Evaluation 27 test, Charlson Comorbidity Index, and American Society of Anesthesiology score. Postoperative complications were dichotomized, and multiple logistic regression was used for data analysis.

Results  Medical chart review identified 157 cases. Analysis of data revealed that time under general anesthesia was the only factor consistently related to complications (P<.006), and it was the only factor consistently related to length of stay (P<.001). Analysis of major complications (6% incidence) as an outcome using univariate analysis resulted in a strong positive correlation with both comorbidity indexes: Adult Comorbidity Evaluation 27 (P = .002) and Charlson Comorbidity Index (P = .005). Multiple logistic regression showed no significant relationship between age 70 years or older (20% of patients) and either complications or hospital length of stay.

Conclusions  Patient’s age alone is not a prognostic indicator of surgical outcome for major head and neck procedures. However, comorbidity is an important predictive factor for postoperative complications in any age group. Time under general anesthesia showed a statistically significant relationship with complication rate and hospital length of stay in multivariate analyses. Consequently, prevention of complications should focus on optimizing preoperative comorbid conditions.

Author Affiliations: State University of New York Downstate Medical Center, Brooklyn, NY (Drs Boruk, Rosenfeld, and Har-El); and The New York Eye and Ear Infirmary, New York, NY (Dr Chernobilsky).

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