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Michael G. Stewart, MD, MPH; Daniel G. Glaze, MD; Ellen M. Friedman, MD; E. O’Brian Smith, PhD; Marilyn Bautista, MPH

Arch Otolaryngol Head Neck Surg. 2005;131:308-314.

Objectives  To assess polysomnogram (PSG) results and global and disease-specific quality of life (QOL) in children with obstructive sleep apnea (OSA), before and after adenotonsillectomy, and to assess the association between PSG findings and QOL.

Design  Prospective observational study. We performed overnight PSG using standardized techniques and assessed disease-specific and global QOL using validated instruments. Follow-up was assessed at 1 year. We compared QOL outcomes between children who underwent adenotonsillectomy and children who did not.

Setting  A large tertiary care children’s hospital.

Patients  Children with sleep-disordered breathing who were suspected of having OSA.

Intervention  Adenotonsillectomy.

Main Outcome Measures  We evaluated PSG parameters, disease-specific QOL, and global QOL.

Results  We enrolled 47 children, 31 of whom met PSG criteria for OSA. Disease-specific and global QOL were not significantly different between children with OSA and children without. Global QOL was significantly worse for children with OSA than healthy children on several subscales: general health perception, behavior, and parental impact–emotional. Children who underwent adenotonsillectomy had significant improvements in QOL scores and PSG parameters (apnea-hypopnea index, P = .004; minimum saturation, P = .004). We found significantly larger QOL changes in children who underwent surgery compared with children without surgery (subscales: infections, P = .01; airway, P = .002; swallowing, P = .02; and behavior, P = .03). No strong association was identified between QOL scores and PSG parameters.

Conclusions  Children with OSA and sleep-disordered breathing have significantly worse QOL than healthy children. However, the association between PSG findings and QOL was only moderate. Children with OSA treated with adenotonsillectomy demonstrated large improvements in disease-specific and global QOL as well as PSG parameters.

Author Affiliations: The Bobby R. Alford Department of Otorhinolaryngology & Communicative Sciences (Drs Stewart and Friedman and Ms Bautista), Department of Pediatrics-Neurology (Dr Glaze), and Department of Pediatrics-Nutrition (Dr Smith), Baylor College of Medicine, Houston, Tex.

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