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Helicobacter pylori in Children Who Are Prone to Upper Respiratory Tract Infections
Anne Pitkäranta, MD;
Kaija-Leena Kolho, MD;
Hilpi Rautelin, MD
Arch Otolaryngol Head Neck Surg. 2005;131:256-258.
Objective To examine the presence of Helicobacter pylori infection in children with recurrent upper respiratory infections, including acute otitis media.
Design A prospective clinical trial.
Setting Tertiary referral center.
Patients A total of 20 children who were prone to upper respiratory infections and acute otitis and who were admitted for elective adenoidectomy and/or tympanostomy were included in the study.
Main Outcome Measures Samples of adenoid tissue and middle ear fluid were cultured for H pylori. Serologic analysis and fecal antigen detection testing were also carried out to determine the presence of H pylori.
Results The results of serologic and antigen detection tests were positive for H pylori in 4 children (20%), but cultures of adenoid tissue and middle ear fluid samples were negative for H pylori in all children.
Conclusion An association between H pylori infection and recurrent upper respiratory infections and otitis media could not be established.
Author Affiliations: Departments of Otorhinolaryngology (Dr Pitkäranta) and Bacteriology and Immunology (Dr Rautelin), Haartman Institute and HUSLAB, and Hospital of Children and Adolescents (Dr Kolho), Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.
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