This Article  • Full text  • PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (5)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Neurology  • Neuro-otology  • Hearing Loss/ Deafness  • Alert me on articles by topic  Social Bookmarking   What's this?

Shin-ichiro Kitajiri, MD; Keisaku Tabuchi, MD; Harukazu Hiraumi, MD; Tomoko Hirose, MD

Arch Otolaryngol Head Neck Surg. 2002;128:365-367.

Objective  To assess the efficacy of corticosteroid therapy for sudden-onset sensorineural hearing loss at lower frequencies.

Design  Retrospective, nonrandomized, controlled study.

Patients and Methods  The recovery rate, recovery/improvement rate, and period between the start of therapy and improvement of symptoms were studied in 2 groups: the control group, consisting of 36 patients treated with adenosine triphosphate disodium, kallidinogenase, and cyanocobalamin between March 1, 2000, and January 31, 2001; and the corticosteroid-treated group, consisting of 42 patients treated with corticosteroids in addition to the previously mentioned drugs between April 1, 1997, and February 29, 2000.

Results  No significant difference (P = .83) was noted in the recovery rate between the control group (81%) and the corticosteroid-treated group (79%), and the recovery/improvement rate was the same for the 2 groups (83%). In addition, there was no significant difference (P = .84) for the mean ± SD period between the start of therapy and improvement of symptoms between the control group (3.9 ± 2.7 days) and the corticosteroid-treated group (3.7 ± 2.1 days).

Conclusion  Corticosteroids were not effective for sudden-onset sensorineural hearing loss at lower frequencies.

From the Department of Otolaryngology–Head and Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto (Dr Kitajiri); the Tabuchi ENT Clinic, Kobe City, Hyogo (Dr Tabuchi); and the Department of Otolaryngology, Toyooka Hospital, Toyooka City, Hyogo (Drs Hiraumi and Hirose), Japan.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Archives of Otolaryngology–Head & Neck Surgery Reader's Choice: Continuing Medical Education
Arch Otolaryngol Head Neck Surg. 2002;128(4):465-466.
FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Steroids in sudden sensorineural hearing loss
Ghosh and Jackson
Emerg. Med. J. 2005;22:732-733.
ABSTRACT | FULL TEXT