Bilateral Vocal Fold Paresis and Multiple System Atrophy
Joel H. Blumin, MD;
Gerald S. Berke, MD
Arch Otolaryngol Head Neck Surg. 2002;128:1404-1407.
Objective To review a case series of patients with systemic neurodegenerative disease presenting to a laryngologist for workup of dysphonia and found to have bilateral vocal fold paresis.
Design Case series.
Setting Tertiary care voice center.
Patients Series of patients with neurodegenerative disorders examined for dysphonia.
Main Outcome Measures History and physical examination including fiberoptic laryngoscopy were performed on all patients. Some patients underwent polysomnography.
Results Seven patients during a 2-year period were noted to have bilateral abductor vocal fold paresis. Five of 7 (71%) had the diagnosis of multiple system atrophy proposed by the laryngologist. All 7 patients described sleep-disordered breathing with stridor.
Conclusions Patients with systemic neurodegenerative disorders such as Parkinson disease should be examined for multiple system atrophy and for evidence of bilateral vocal fold paresis. Workup for stridor should include polysomnography. Treatment of glottic obstruction in these patients includes constant positive airway pressure at night or tracheotomy. The finding of bilateral vocal fold paresis can be life threatening.
From the PENN Center for Voice, Department of Otorhinolaryngology–Head and Neck Surgery, University of Pennsylvania School of Medicine, Philadelphia (Dr Blumin); and Division of Head and Neck Surgery, University of California, Los Angeles, UCLA School of Medicine (Dr Berke).
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