
Squamous Cell Carcinoma of the Temporal Bone
A Radiographic-Pathologic Correlation
M. Boyd Gillespie, MD;
Howard W. Francis, MD;
Nelson Chee, MD;
David W. Eisele, MD
Arch Otolaryngol Head Neck Surg. 2001;127:803-807.
Objective To assess the utility of a previously proposed staging system for patients
with primary squamous cell carcinoma of the temporal bone.
Methods Retrospective chart review of 15 patients treated for squamous cell
carcinoma of the temporal bone over a 13-year period at an academic tertiary
referral center. A review of the medical and surgical records, radiographic
studies, and surgical pathology reports allowed for an evaluation of the University
of Pittsburgh staging system. Outcome analysis was performed on 13 patients
with more than 24 months of follow-up.
Results Radiographic and surgical pathology staging according to the University
of Pittsburgh staging system correlated in 11 (73%) of 15 cases. The radiographic
staging system was more accurate for larger (T3/T4) tumors than for smaller
(T1/T2) tumors (83% vs 67%). When compared with patients with no evidence
of disease, nonsurvivors were more likely to present with otalgia (67% vs
43%), facial nerve paralysis (33% vs 0%), and T3/T4 tumors (100% vs 14%).
Conclusions Pathologic staging by the University of Pittsburgh staging system closely
correlates with patient outcome and is more sensitive than preoperative radiographic
staging. Prognosis in squamous cell carcinoma of the temporal bone is largely
determined by the extent of local disease at the time of presentation.
From the Departments of OtolaryngologyHead and Neck Surgery,
The Medical University of South Carolina, Charleston (Dr Gillespie), and The
Johns Hopkins University School of Medicine, Baltimore, Md (Drs Francis, Chee,
and Eisele).
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