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Intraoperative Microwave Processing of Bone Margins During Resection of Head and Neck Cancer
Edward C. Weisberger, MD;
Matthew Hilburn, MD;
Bradley Johnson, HT (ASCP);
Charly Nguyen, MD
Arch Otolaryngol Head Neck Surg. 2001;127:790-793.
Objective To develop an accurate method for performing histopathologic analysis
for a full cross-section of cortical bone within 2 to 3 hours.
Methods Microwave technology was used to augment and to more rapidly perform
fixation and decalcification of cortical bone.
Results Using the methods described, slides suitable for hispathologic analyses
regarding the presence or absence of malignant tumor were prepared in 2 to
3 hours and, in 10 patients studied, had a 100% correlation with slides prepared
in 7 days using the standard decalcification technique.
Conclusion Microwave technology allows accurate assessment of a full cross-section
of cortical bone regarding the presence or absence of malignant tumor within
the time limits required for resection of a malignant head and neck tumor
and reconstruction of the surgical defect.
From the Departments of Otolaryngology–Head and Neck Surgery
(Dr Weisberger), Surgery (Dr Hilburn), and Pathology (Mr Johnson), Indiana
University Medical Center, Indianapolis. Dr Nguyen is in private practice
in Mattoon, Ill.
RELATED ARTICLE
Archives of Otolaryngology–Head & Neck Surgery Reader's Choice: Continuing Medical Education
Arch Otolaryngol Head Neck Surg. 2001;127(7):889-890.
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