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Yongqing Guo, MD; Yuichi Majima, MD; Masahiko Hattori, MD; Shinji Seki, MD; Yasuo Sakakura, MD

Arch Otolaryngol Head Neck Surg. 1997;123(10):1097-1100.

Abstract
Objective
To compare the preoperative and postoperative changes on ciliary surface of maxillary sinus mucosa in patients treated with functional endoscopic sinus surgery.

Design
The maxillary mucosa of both the superolateral wall and the ostium were sampled during the operation and 6 to 12 months (mean duration, 7.6 months) after the operation. Ciliary surface was determined using scanning electron microscopy in combination with an image analyzer and was expressed in terms of ciliary area, which is the percentage of mucosal surface occupied by cilia.

Setting
The samples were taken at a hospital-based clinic. An electron microscopic study was performed at Mie University School of Medicine, Mie, Japan.

Patients
Sixteen patients (20 maxillary sinuses) undergoing functional endoscopic sinus surgery for treatment of chronic sinusitis.

Results
The mean (±SD) ciliary area before the surgery was 60.7%±28.8% and 39.9%±21.5% in the superolateral wall of the maxillary sinus and the ostium of the maxillary sinus, respectively. The ciliary area of the superolateral wall was significantly higher than that of the ostium (P<.001). The mean (±SD) postoperative ciliary area value was 74.3% ± 22.6% in the superolateral wall and 51.3%± 16.1% in the ostium. These postoperative values were significantly higher than the preoperative values (P<.001).

Conclusions
This study showed that the maxillary sinus mucosa in chronic sinusitis is capable of regeneration, and the damaged ciliated epithelium could return toward normal with the improvement of ventilation and drainage of the maxillary sinus following functional endoscopic sinus surgery.

Arch Otolaryngol Head Neck Surg. 1997;123:1097-1100

Author Affiliations
From the Department of Otorhinolaryngology, Mie University School of Medicine, Tsu, Mie (Drs Guo, Majima, and Sakakura), and Seki Hospital, Mishima, Shizuoka (Drs Hattori and Seki), Japan.

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