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Jennifer H. Judkins, MD; Todd G. Dray, MD; Richard N. Hubbell, MD

Arch Otolaryngol Head Neck Surg. 1996;122(9):937-940.

Abstract
Objective
To determine the occurrence of posttonsillectomy bleeding in patients who received intraoperative ketorolac tromethamine.

Design
Retrospective analysis.

Setting
Academic tertiary care center.

Patients
Three hundred eleven patients who underwent tonsillectomy in an 18-month period.

Main Outcome Measure
Occurrence of bleeding complications in patients who received ketorolac during tonsillectomy.

Results
Fifty-eight of 311 patients who underwent tonsillectomy received intraoperative ketorolac with an overall postoperative bleeding rate of 17%. This high rate of bleeding complications compares with 4.4% in the remaining 253 patients who received traditional opioid analgesics.

Conclusions
Until further controlled studies have been conducted, the use of ketorolac in patients undergoing tonsillectomy should be avoided because of the increased incidence of postoperative bleeding complications.

Arch Otolaryngol Head Neck Surg. 1996;122:937-940

Author Affiliations
From the Division of Otolaryngology, Department of Surgery, University of Vermont, Burlington (Drs Judkins, Dray, and Hubbell); and the Department of Otolaryngology, State University of New York—Brooklyn (Dr Judkins).

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