This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Linda L. D'Antonio, PhD; Grenith J. Zimmerman, PhD; David F. Cella, PhD; Steven A. Long, MD

Arch Otolaryngol Head Neck Surg. 1996;122(5):482-487.

Abstract
Objective
To assess the relationship among three validated head and neck—specific measures of functional status and a general measure of quality of life in patients with head and neck cancer.

Design
Cross-sectional study using medical chart review, patient interview, and test administration.

Setting
Academic tertiary referral center.

Participants
Fifty adult patients 3 months to 6 years after major surgery for head and neck cancer.

Main Outcome Measure
Scores from a general measure of quality of life (the Functional Assessment of Cancer Therapy), a subscale specific to head and neck cancer, the University of Washington Quality of Life

Questionnaire, and the Performance Status Scale for Head and Neck Cancer Patients.

Results
The disease-specific measures of functional status correlate well with one another. However, there were low correlations between the Functional Assessment of Cancer Therapy and the disease-specific measures, indicating that general and disease-specific instruments contribute unique information about quality of life.

Conclusion
A general measure of quality of life augments information obtained by disease-specific instruments by interpreting functional status in the broader scope of the patient's life.

(Arch Otolaryngol Head Neck Surg. 1996;122:482-487)

Author Affiliations
From the School of Medicine and Cancer Institute (Dr D'Antonio), School of Allied Health (Dr Zimmerman), and Medical Center (Dr Long), Loma Linda (Calif) University; and Rush-Presbyterian-St Luke's Medical Center, Chicago, Ill (Dr Cella).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Outcome Measures in Facial Plastic Surgery: Patient-Reported and Clinical Efficacy Measures
Rhee and McMullin
Arch Facial Plast Surg 2008;10:194-207.
ABSTRACT | FULL TEXT  

Patient-Reported Outcomes in Phase II Cancer Clinical Trials: Lessons Learned and Future Directions
Wagner et al.
JCO 2007;25:5058-5062.
ABSTRACT | FULL TEXT  

Quality-of-Life Assessment After Supradose Selective Intra-arterial Cisplatin and Concomitant Radiation (RADPLAT) for Inoperable Stage IV Head and Neck Squamous Cell Carcinoma
Ackerstaff et al.
Arch Otolaryngol Head Neck Surg 2002;128:1185-1190.
ABSTRACT | FULL TEXT  

Assessing Quality of Life in Patients With Head and Neck Cancer: Cross-validation of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Head and Neck Module (QLQ-H&N35)
Sherman et al.
Arch Otolaryngol Head Neck Surg 2000;126:459-467.
ABSTRACT | FULL TEXT