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A Prospective, Double-blind, Randomized Study of the Effects of Perioperative Steroids on Palatoplasty Patients
Craig W. Senders, MD;
Brian E. Emery, MD;
Jonathan M. Sykes, MD;
Hilary A. Brodie, MD, PhD
Arch Otolaryngol Head Neck Surg. 1996;122(3):267-270.
Abstract
Objective
To determine whether perioperative steroids affect the outcome of patients who undergo palatoplasty.
Design
A prospective, double-blind, randomized study.
Setting
A university medical center.
Patients
Twenty patients undergoing primary repair of a cleft palate.
Intervention
A prospective double-blind technique was used to randomly assign patients to receive a placebo or dexamethasone sodium phosphate perioperatively.
Main Outcome Measure
Patients were monitored for postoperative airway distress, fever, oral fluid intake, days of hospitalization, and wound healing.
Results
The use of perioperative steroids was associated with shorter hospitalizations. No adverse sequelae from the administration of steroids were identified.
Conclusion
In our current managed care environment, the use of perioperative steroids may play an important role in reducing health care costs.
(Arch Otolaryngol Head Neck Surg. 1996;122:267-270)
Author Affiliations
From the Department of Otolaryngology–Head and Neck Surgery, University of California, Davis, Medical Center (Drs Senders, Sykes, and Brodie), and the Division of Otolaryngology–Head and Neck Surgery, University of Maryland Medical Center, Baltimore (Dr Emery).
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ABSTRACT
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