Metastatic Melanoma to the Cerebellopontine AngleClinical and Imaging Characteristics
Moises A. Arriaga, MD;
William W. M. Lo, MD;
Derald E. Brackmann, MD
Arch Otolaryngol Head Neck Surg. 1995;121(9):1052-1056.
Abstract
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Objective
To describe the clinical and imaging features of metastatic melanoma to the cerebellopontine angle (CPA).
Design
A case series study with world literature review.
Setting
House Ear Clinic and St Vincent's Hospital, Los Angeles, Calif.
Patients
Three cases of metastatic CPA tumors operated on at the House Ear Clinic.
Interventions
All patients underwent surgical removal of CPA metastatic melanoma.
Main Outcome Measure
Survival and duration of disease-free interval are reported.
Results
Two patients died of melanoma within 5 months of diagnosis and resection of CPA melanoma metastases. One patient survived for 5 years after undergoing total resection of an isolated CPA melanoma metastasis. Magnetic resonance imaging features were not uniform.
Conclusions
Metastatic melanoma to the CPA should be suspected in patients with a history of melanoma and a rapid progression of audiovestibular or facial nerve symptoms. Surgical removal of solitary metastases to the CPA may be valuable in patients without other melanoma focus; however, the longterm prognosis for patients with CPA melanoma is grim.
(Arch Otolaryngol Head Neck Surg. 1995;121:1052-1056)
Author Affiliations
From the Department of Otolaryngology, Wilford Hall Air Force Medical Center, Lackland Air Force Base, Tex (Dr Arriaga); the Department of Radiology, St Vincent Medical Center, Los Angeles, Calif (Dr Lo); and the House Ear Clinic, University of Southern California, Los Angeles (Dr Brackmann).
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