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Jef J. S. Mulder, MD; Cor W. R. J. Cremers, MD, PhD; Frank Joosten, MD; Anne Wiersma, MD; Paul van den Broek, MD, PhD

Arch Otolaryngol Head Neck Surg. 1995;121(8):930-933.

Abstract
We describe three cases of a fibroinflammatory pseudotumor (tumefactive fibroinflammatory lesion) of the middle and inner ear. The patients presented with total deafness in the affected ear and no response to caloric stimulation. The computed tomographic pattern showed destruction of inner ear structures and a typical widening of parts of the labyrinth. Magnetic resonance imaging performed in all three patients showed an extension greater than expected based on computed tomographic images of both areas of destruction, as well as areas of radiologic normality. An enhancing mass was seen in the inner ear with a characteristic extension into both the internal auditory canal and the middle ear. A transotic approach or subtotal petrosectomy was used to remove the tumor in all three cases. Although histologically benign, these tumors are locally destructive and, as such, behave like a neoplastic lesion. They are composed of fibrovascular tissue admixed with chronic inflammatory cells. To our knowledge, this is the first report on pseudotumors of the middle ear, inner ear, and internal auditory canal. Inflammatory pseudotumor used to be a somewhat confusing term for a recognized entity of unknown origin. It is likely that infection is an important contributing factor in the development of these lesions. Although surgical removal seems to be the treatment of choice, no clear judgment of its prognosis can be made owing to the rarity of this tumor.

(Arch Otolaryngol Head Neck Surg. 1995;121:930-933)

Author Affiliations
From the Departments of Otorhinolaryngology—Head and Neck Surgery (Drs Mulder, Cremers, and van den Broek), Radiology (Dr Joosten), and Pathology (Dr Wiersma), Radboud University Hospital, Nijmegen, the Netherlands.

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