Acquired Laryngeal LesionsPathologic Study Using Serial Macrosections
Jiann-Chyuan Chen, MD;
Lauren D. Holinger, MD
Arch Otolaryngol Head Neck Surg. 1995;121(5):537-543.
Abstract
Objective
To present the pathologic findings of acquired lesions of the larynx in infants.
Setting
The Laryngeal Development Laboratory of Children's Memorial Hospital, Chicago, Ill.
Materials
One hundred fifteen larynges received at postmortem examination from 1975 to 1992.
Main Outcome Measure
Acquired laryngeal lesions from intubation trauma.
Technique
Whole-organ serial section of larynges.
Results
Fifty-three of the 115 specimens exhibited acquired laryngeal lesions: 36, submucosal mucous gland hyperplasia; 12, submucosal fibrosis; 10, granulation tissue; eight, ulceration; eight, fragmented or distorted cricoid; four, cricoid ossification; four, ductal cysts; three, healed furrows, and one, anterior glottic synechia. Some specimens exhibited more than one type of acquired abnormality.
(Arch Otolaryngol Head Neck Surg. 1995;121:537-543)
Author Affiliations
From the Department of Otolaryngology, National Taiwan University Hospital, Taipei (Dr Chen); and the Division of Pediatric Otolaryngology, Children's Memorial Hospital, and the Department of Otolaryngology—Head and Neck Surgery, Northwestern University Medical School, Chicago, Ill (Dr Holinger).
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