This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

W. Frederick McGuirt, MD; David Blalock, MA; James A. Koufman, MD; Robert S. Feehs, MD; Anita J. Hilliard, MD; Kathy Greven, MD; Mark Randall, MD

Arch Otolaryngol Head Neck Surg. 1994;120(9):951-955.

Abstract
Objective
To compare voice results following laser resection or radiation therapy for T1a glottic carcinomas.

Design
Objective recordings of acoustical data that were analyzed and calculated by an acoustic analyzer and subjective scores by patients, speech therapists, surgeons, and radiation therapists are compared.

Setting
Academic medical center speech laboratory at an institution where patients had been treated. Archival files were searched and patients were solicited by letter to participate in this analysis.

Patients
Men treated at least 6 months previously and who were without active laryngeal disease. Criteria were unilateral vocal cord carcinomatous involvement with no subglottic, anterior commissure, or arytenoid extension and tumor invasion clinically judged to be less than half of the cordal depth.

Interventions
Thirteen patients had received approximately 63 Gy in 28 fractions, five fractions a week, with laterally opposed fields using a linear accelerator. Eleven patients had had resection of less than half of the cordal depth by using a carbon dioxide laser with a 300-µm spot size working at a 400-mm distance; 13- to 15-W power intensity with a one tenth of a second burn in a noncontinuous mode.

Results
No statistically significant differences between the two study groups were found. Patients and physicians subjectively rated (1 indicates normal; 5, aphonic) the quality of voices of patients in the irradiation group (1.5 and 2.0) as slightly better than the quality of voices of patients in the laser group (2.0 and 2.4). Speech pathologists rated the voices of patients in the laser and irradiation group as indistinguishable and mildly abnormal (2.75 and 2.73).

Conclusion
Voice quality in highly selected patients with vocal cord carcinoma treated by laser resection can be as good as that in patients whose cancer was similarly staged after radiation therapy.

(Arch Otolaryngol Head Neck Surg. 1994;120:951-955)

Author Affiliations
From the Departments of Otolaryngology (Drs McGuirt, Koufman, and Feehs), Hearing and Speech (Mr Blalock), and Radiation Therapy (Drs Greven and Randall), The Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Voice-Related Quality of Life After Treatment of Laryngeal Cancer
Oridate et al.
Arch Otolaryngol Head Neck Surg 2009;135:363-368.
ABSTRACT | FULL TEXT  

Efficacy of Concurrent Chemoradiotherapy for T1 and T2 Laryngeal Squamous Cell Carcinoma Regarding Organ Preservation
NISHIMURA et al.
Anticancer Res 2009;29:661-666.
ABSTRACT | FULL TEXT  

Voice Outcome in T1a Midcord Glottic Carcinoma: Laser Surgery vs Radiotherapy
Sjogren et al.
Arch Otolaryngol Head Neck Surg 2008;134:965-972.
ABSTRACT | FULL TEXT  

Vocal outcomes after laser resection of early-stage glottic cancer with adjuvant cryotherapy.
Knott et al.
Arch Otolaryngol Head Neck Surg 2006;132:1226-1230.
ABSTRACT | FULL TEXT  

American Society of Clinical Oncology Clinical Practice Guideline for the Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer
Pfister et al.
JCO 2006;24:3693-3704.
ABSTRACT | FULL TEXT  

Voice and Swallowing in Patients Enrolled in a Larynx Preservation Trial
Carrara-de Angelis et al.
Arch Otolaryngol Head Neck Surg 2003;129:733-738.
ABSTRACT | FULL TEXT  

Voice Quality After Radiation Therapy for Early Glottic Cancer
Honocodeevar-Boltezar and Zargi
Arch Otolaryngol Head Neck Surg 2000;126:1097-1100.
ABSTRACT | FULL TEXT  

Acoustic and Perceptual Evaluation of Voice and Speech Quality: A Study of Patients With Laryngeal Cancer Treated With Laryngectomy vs Irradiation
Finizia et al.
Arch Otolaryngol Head Neck Surg 1999;125:157-163.
ABSTRACT | FULL TEXT  

Assessing Vocal Function After Chemoradiation for Advanced Laryngeal Carcinoma
Woodson et al.
Arch Otolaryngol Head Neck Surg 1996;122:858-864.
ABSTRACT