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George A. Gates, MD; George O. Sertl, MD; Robert L. Grubb, MD; Franz J. Wippold, II, MD

Arch Otolaryngol Head Neck Surg. 1994;120(4):459-461.

Abstract
Cerebrospinal fluid fistula into the upper airway often results in meningitis. Closure of fistulas is usually effective using conventional surgical techniques to reconstruct the defect. We report a case of cerebrospinal fluid fistula into the sphenoid sinus and nasopharynx secondary to resection of a clivus chordoma that resisted conventional attempts at closure, including a rectus abdominus free flap. Closure of the fistula was accomplished with the use of a novel alloplast, biocompatible osteoconductive polymer. Follow-up for more than 1 year shows no evidence of rejection, infection, or recurrent cerebrospinal fluid rhinorrhea.

(Arch Otolaryngol Head Neck Surg. 1994;120:459-461)

Author Affiliations
From Washington University, St Louis, Mo.

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