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A New Treatment

Philip S. Mehler, MD; James A. Wallace, RPH

Arch Otolaryngol Head Neck Surg. 1993;119(7):787-788.

Abstract
• Objective.
—To see whether a cholinomimetic medication would help resolve the parotid gland enlargement associated with self-induced vomiting in bulimic patients.

Setting/Design.
—The medication was administered on an inpatient eating disorder unit to bulimic patients with refractory sialadenosis.

Intervention.
—Pilocarpine hydrochloride drops were administered orally at a dosage of 1.25 to 5.0 mg/d until the parotid gland enlargement was significantly reduced.

Results.
—There was a marked diminution in the size of the parotid gland enlargement.

Conclusion.
—Pilocarpine has proved to be beneficial in the treatment of sialadenosis in bulimic patients.

(Arch Otolaryngol Head Neck Surg. 1993;119:787-788)

Author Affiliations
From the Departments of Internal Medicine (Dr Mehler) and Pharmacy (Mr Wallace), Columbine Hospital, Littleton, Colo, and the Department of Medicine, University of Colorado Health Sciences Center, Denver (Dr Mehler).

Footnotes
Accepted for publication December 30, 1992.

Reprint requests to Department of Internal Medicine, Columbine Hospital, 8565 S Poplar Way, Littleton, CO 80126 (Dr Mehler).

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