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Robert A. Frankenthaler, MD; Robert M. Byers, MD; Mario A. Luna, MD; David L. Callender, MD; Pat Wolf; Helmuth Goepfert, MD

Arch Otolaryngol Head Neck Surg. 1993;119(5):517-520.

Abstract
• To determine the factors predictive of occult cervical metastases, we retrospectively reviewed the charts of 99 previously untreated patients with a primary parotid malignancy who underwent elective neck dissection between 1960 and 1985. Univariate and multivariate analyses were performed to determine the predictive value of 11 factors. The univariate study found facial nerve paralysis, extraparotid extension, and perilymphatic invasion statistically significant. In the multivariate analysis of preoperative factors, facial nerve paralysis was most predictive of occult disease. If the variable pool was expanded to include a fine-needle biopsy, tumor grade became the most important preoperative variable. When the analysis was further expanded to include a parotidectomy, the most influential factors were patient age, perilymphatic invasion, and extraparotid tumor extension. This report identifies the variables predictive of occult neck disease in parotid cancer.

(Arch Otolaryngol Head Neck Surg. 1993;119:517-520)

Author Affiliations
From the Departments of Head and Neck Surgery (Drs Frankenthaler, Byers, Callender, and Goepfert and Ms Wolf) and Pathology (Dr Luna), The University of Texas M. D. Anderson Cancer Center, Houston.

Footnotes
Accepted for publication November 18, 1992.

Presented in part at the Third International Conference on Head and Neck Surgery, San Francisco, Calif, July 26, 1992.

Reprint requests to Department of Head and Neck Surgery, The University of Texas M. D.Anderson Cancer Center, Box 69, 1515 Holcombe Blvd, Houston, TX 77030 (Dr Frankenthaler).

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