This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Duncan McRae, FRCS; George Buchanan, FRCS

Arch Otolaryngol Head Neck Surg. 1993;119(1):103-105.

Abstract
• Since 1985, a number of reports have highlighted the effectiveness of a short course of sulfamethoxazole-trimethoprim as an adjuvant to immunosuppressive drugs in the treatment of Wegener's granulomatosis. We report our experience with long-term sulfamethoxazole-trimethoprim therapy in patients with Wegener's granulomatosis. We describe recent advances in the pathogenesis of Wegener's granulomatosis, suggest a complementary mechanism of action of sulfamethoxazole-trimethoprim, and advocate long-term sulfamethoxazole-trimethoprim therapy as a treatment option in Wegener's granulomatosis.

(Arch Otolaryngol Head Neck Surg. 1993;119:103-105)

Author Affiliations
From the Ear, Nose, and Throat Department, Southend Hospital, Westcliff-on-Sea, England. Dr McRae is now with the Ear, Nose, and Throat Department, The Royal London (England) Hospital.

Footnotes
Accepted for publication August 20, 1992.

Reprints not available.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?