This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

William Ignace Wei, MBBS, MS, FRCSE, DLO; Chiu Ming Ho, MBBS, FRCSE, FRACS; Maria Pik Wong, MBBS, MRCP, MRCP(Path); Wing Fung Ng, MBBS, MRCP, MRCP(Path); Sai Kit Lau, MBBS, DLO, FRCSE; Kam Hing Lam, MBBS, MS, FRCSE, FRACS

Arch Otolaryngol Head Neck Surg. 1992;118(9):923-929.

Abstract
• Radical neck dissection was performed on 43 patients with nasopharyngeal carcinoma in whom persistent or recurrent cervical metastasis developed after radiotherapy. The pathologic nature of the tumor in the cervical lymph nodes was studied with step serial sectioning of the entire radical neck dissection specimen at 3-mm intervals. In 70% of patients, more tumor-harboring lymph nodes were detected in the specimen when compared with clinical examination. The extensive behavior of the tumor in the cervical metastases was reflected by the presence of extracapsular spread in 70% of the lymph nodes and the existence of isolated clusters of tumor cells in 35% of the specimens studied. Tumor tissue lying in close proximity to the spinal accessory nerve was demonstrated in 27.5% of the specimens, and 72% of the tumor-bearing lymph nodes were located in the posterior triangle. Radical neck dissection is recommended as the salvage procedure for these patients.

(Arch Otolaryngol Head Neck Surg. 1992;118:923-929)

Author Affiliations
From the Departments of Surgery (Drs Wei, Ho, Lau, and Lam) and Pathology (Drs Wong and Ng), The University of Hong Kong, Queen Mary Hospital, Hong Kong.

Footnotes
Accepted for publication April 7, 1992.

Reprint requests to Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong (Dr Wei).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Management of Extensive Cervical Nodal Metastasis in Nasopharyngeal Carcinoma After Radiotherapy: A Clinicopathological Study
Wei et al.
Arch Otolaryngol Head Neck Surg 2001;127:1457-1462.
ABSTRACT | FULL TEXT  

Nasopharyngeal Cancer: Current Status of Management: A New York Head and Neck Society Lecture
Wei
Arch Otolaryngol Head Neck Surg 2001;127:766-769.
ABSTRACT | FULL TEXT  

Salvage Neck Dissection for Cervical Recurrence of Nasopharyngeal Carcinoma
Yen et al.
Arch Otolaryngol Head Neck Surg 1997;123:725-729.
ABSTRACT  

Surgery in the Management of Postradiotherapy Cervical Metastasis
BATSAKIS
Arch Otolaryngol Head Neck Surg 1992;118:930-930.
ABSTRACT